SCHEMBL2864627

SCHEMBL2864627

Cc1ccc2c(c1)C([Zr](Cl)(Cl)(=C(c1ccccc1)c1ccccc1)C1c3cc(C)ccc3-c3ccc(C)cc31)C=C2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2861112 0.94 LMNA (0.31) LMNASMN1; SMN2
SCHEMBL2869717 0.94 LMNA (0.31) LMNASMN1; SMN2
SCHEMBL2872419 0.94
SCHEMBL2860912 0.92 LMNA (0.30) LMNASMN1; SMN2
SCHEMBL2860954 0.92 LMNA (0.33) LMNASMN1; SMN2
SCHEMBL2860239 0.92
SCHEMBL2866135 0.92
SCHEMBL2864706 0.87 POLB (0.32)
SCHEMBL2860603 0.87
SCHEMBL2862478 0.85 S1PR4 (0.32) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed