SCHEMBL28646384

SCHEMBL28646384

OC(C=CBr)c1ccc(F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.36
IDO1 P14902 2/20 0.35
TDO2 P48775 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
APEX1 P27695 1/20 0.34
MRGPRX1 Q96LB2 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29059960 0.78 AOC3 (0.36) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL8773918 0.78 MEN1 (0.52) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL4121060 0.75 AOC3 (0.38) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL4121057 0.75 AOC3 (0.38) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL7057351 0.75 AOC3 (0.38) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL11981277 0.75 AOC3 (0.38) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL7057353 0.75 AOC3 (0.38) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL3885072 0.73 ORAI1 (0.42) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL15833075 0.73 HDAC3 (0.42) AOC3IDO1TDO2HDAC3HDAC4
SCHEMBL1712779 0.73 HDAC3 (0.42) AOC3IDO1TDO2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429249-B Method for synthesizing chiral 4-hydroxy amino acid derivative 陕西师范大学 2023-06-16 CN disclosed
CN-113429249-A Method for synthesizing chiral 4-hydroxy amino acid derivative 陕西师范大学 2021-09-24 CN disclosed