Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 5/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308515 | 0.81 | — | — | |
| SCHEMBL9624068 | 0.81 | POLB (0.54) | TEAD1SMYD3POLBEPHX1EPHX2 | |
| SCHEMBL18752837 | 0.79 | TEAD1 (0.45) | TEAD1SMYD3POLBEPHX1BTK | |
| SCHEMBL18753607 | 0.79 | TEAD1 (0.45) | TEAD1SMYD3POLBEPHX1BTK | |
| SCHEMBL24492194 | 0.79 | TEAD1 (0.50) | TEAD1SMYD3POLBEPHX2JAK3 | |
| SCHEMBL5263260 | 0.78 | EPHX1 (0.41) | SMYD3POLBEPHX1EPHX2NPC1 | |
| SCHEMBL5263263 | 0.78 | EPHX1 (0.41) | SMYD3POLBEPHX1EPHX2NPC1 | |
| SCHEMBL22660898 | 0.77 | POLB (0.47) | TEAD1SMYD3POLBBTKEPHX2 | |
| SCHEMBL30716262 | 0.77 | POLB (0.42) | TEAD1SMYD3POLBBTKHTT | |
| SCHEMBL19409139 | 0.76 | POLB (0.45) | TEAD1SMYD3POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490666-A | Substituted pyrazolo [1,5-A ] pyridine compounds as inhibitors of FGFR tyrosine kinases | 奥瑞生物药品公司 | 2021-10-08 | — | — | CN | disclosed |