Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Anthranilic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthranilic Acid SCHEMBL29365173 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Anthranilic Acid SCHEMBL29802554 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Anthranilic Acid SCHEMBL3110791 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Anthranilic Acid SCHEMBL2953168 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Anthranilic Acid SCHEMBL675 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Anthranilic Acid SCHEMBL362171 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Anthranilic Acid SCHEMBL2961107 | 0.91 | ALDH1A1 (0.65) | MAPTGAANAPRTMMP2ALDH1A1 | |
| Aminobenzoic Acid SCHEMBL1319387 | 0.90 | MAPT (0.55) | MAPTGAATSHRNAPRTDAO | |
| Aminobenzoic Acid SCHEMBL2717855 | 0.90 | MAPT (0.55) | MAPTGAATSHRNAPRTDAO | |
| Anthranilic Acid SCHEMBL11130666 | 0.89 | ALDH1A1 (0.62) | MAPTGAANAPRTMMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613495-A | Compositions comprising fluorochloropyrimidin and other herbicides and methods thereof | 美国陶氏益农公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113271777-A | Compositions comprising fluorochloropyrimidin and other herbicides and methods thereof | 美国陶氏益农公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-113271776-A | Compositions comprising fluorochloropyrimidin and other herbicides and methods thereof | 美国陶氏益农公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-107226913-B | Frame coordination material with tetranuclear cobalt as node and preparation method thereof | 江汉大学 | 2021-03-09 | — | — | CN | disclosed |
| CN-108473528-A | High intensity sweetner | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| US-7794972-B2 | Benzoate-and anthranilate-inducible promoters | PFENEX INC. (US) | 2010-09-14 | — | — | US | disclosed |
| EP-1539794-B1 | BENZOATE- AND ANTHRANILATE-INDUCIBLE PROMOTERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-12-31 | — | — | EP | disclosed |
| EP-1539794-A4 | BENZOATE- AND ANTHRANILATE-INDUCIBLE PROMOTERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20050202544-A1 | Benzoate-and anthranilate-inducible promoters | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-15 | — | — | US | disclosed |
| EP-1539794-A2 | BENZOATE- AND ANTHRANILATE-INDUCIBLE PROMOTERS | Dow Global Technologies Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004005221-A2 | BENZOATE- AND ANTHRANILATE-INDUCIBLE PROMOTERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-01-15 | — | — | WO | disclosed |