Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 9/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647605 | 1.00 | FUCA1 (0.35) | FUCA1ATMCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28630053 | 0.82 | ATM (0.36) | ATM | |
| SCHEMBL28574783 | 0.82 | ATM (0.36) | ATM | |
| SCHEMBL28574784 | 0.82 | ATM (0.36) | ATM | |
| SCHEMBL9929676 | 0.82 | ATM (0.36) | ATM | |
| SCHEMBL28930445 | 0.82 | ATM (0.36) | ATM | |
| SCHEMBL11876881 | 0.81 | CHRM2 (0.38) | FUCA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL15866133 | 0.81 | CHRM2 (0.38) | FUCA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28586291 | 0.79 | CHRNB2 (0.34) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL30738362 | 0.79 | CHRNB2 (0.34) | ATMCHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631557-A | JAK kinase inhibitor, preparation method thereof and application thereof in medical field | 上海华汇拓医药科技有限公司 | 2021-11-09 | — | — | CN | disclosed |