Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 4/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitroacetic Acid SCHEMBL16673169 | 0.97 | LMNA (0.46) | LMNAMEN1BLMHBBKMT2A | |
| Nitroacetic Acid SCHEMBL953175 | 0.97 | LMNA (0.46) | LMNAMEN1BLMHBBKMT2A | |
| Nitroacetic Acid SCHEMBL2263714 | 0.95 | LMNA (0.44) | LMNAMEN1BLMHBBKMT2A | |
| Nitroacetic Acid SCHEMBL28647373 | 0.95 | LMNA (0.44) | LMNAMEN1BLMHBBKMT2A | |
| Nitroacetic Acid SCHEMBL7784649 | 0.95 | LMNA (0.44) | LMNAMEN1BLMHBBKMT2A | |
| Nitroacetic Acid SCHEMBL29086914 | 0.92 | — | — | |
| Nitroacetic Acid SCHEMBL153563 | 0.89 | — | — | |
| Nitroacetic Acid SCHEMBL13859134 | 0.86 | — | — | |
| Nitroacetic Acid SCHEMBL19995636 | 0.86 | LMNA (0.50) | LMNAMEN1BLMHBBKMT2A | |
| Nitroacetic Acid SCHEMBL5933852 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474866-A | Electron microscope grid | 安特卫普大学 | 2021-10-01 | — | — | CN | disclosed |