Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 16/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657015 | 0.89 | TSHR (0.45) | MAP3K5ABL1LMNAHPGD | |
| SCHEMBL28643381 | 0.88 | MAPK1 (0.43) | MAP3K5ABL1LMNA | |
| SCHEMBL28649133 | 0.88 | MAP3K5 (0.44) | MAP3K5ABL1HPGD | |
| SCHEMBL28643374 | 0.84 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL20750911 | 0.84 | MAP3K5 (0.41) | MAP3K5ABL1 | |
| SCHEMBL28660361 | 0.81 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL28658684 | 0.81 | MAP3K5 (0.40) | MAP3K5ABL1 | |
| SCHEMBL23865349 | 0.80 | MAP3K5 (0.48) | MAP3K5 | |
| SCHEMBL28643811 | 0.79 | MAP3K5 (0.43) | MAP3K5ABL1 | |
| SCHEMBL28658681 | 0.78 | TLR2 (0.44) | MAP3K5ABL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400625-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |