Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649619 | 0.95 | TSHR (0.49) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL28549680 | 0.89 | TSHR (0.49) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL28653702 | 0.89 | TSHR (0.49) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL28559340 | 0.88 | TSHR (0.42) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL28560106 | 0.88 | TSHR (0.47) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL284263 | 0.86 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL7682195 | 0.86 | NAAA (0.52) | TSHRNAAAHCAR2EPHX1ATM | |
| SCHEMBL28670410 | 0.85 | TSHR (0.51) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL28558109 | 0.84 | TSHR (0.47) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL7687964 | 0.84 | NAAA (0.55) | TSHRNAAAHCAR2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678997-B | Catalyst component and catalyst for olefin polymerization, prepolymerized catalyst and olefin polymerization method | 中国石油化工股份有限公司 | 2021-11-19 | — | — | CN | disclosed |