Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832839 | 0.98 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2AHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6700297 | 0.95 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2AHPGDL3MBTL1 | |
| Bromide SCHEMBL28648399 | 0.95 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2AHPGDL3MBTL1 | |
| Trimethylammonium SCHEMBL27516176 | 0.92 | SIGMAR1 (0.55) | SIGMAR1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL3871421 | 0.91 | SIGMAR1 (0.65) | SIGMAR1L3MBTL1 | |
| SCHEMBL8441288 | 0.89 | SIGMAR1 (0.69) | SIGMAR1L3MBTL1HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL31261522 | 0.89 | SIGMAR1 (0.63) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL22444738 | 0.89 | SIGMAR1 (0.69) | SIGMAR1L3MBTL1HDAC1HDAC2 | |
| SCHEMBL22444477 | 0.89 | SIGMAR1 (0.69) | SIGMAR1L3MBTL1HDAC1HDAC2 | |
| SCHEMBL11809861 | 0.89 | SIGMAR1 (0.69) | SIGMAR1L3MBTL1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113543752-A | Multi-dose ophthalmic fluid delivery system | 科达莱昂治疗公司 | 2021-10-22 | — | — | CN | disclosed |