Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL28475465 | 0.79 | HTT (0.34) | HTTTBXAS1ALDH1A1NFKB1QPCT | |
| Sulfuric Acid SCHEMBL7939759 | 0.79 | HTT (0.34) | HTTTBXAS1ALDH1A1NFKB1QPCT | |
| Sulfuric Acid SCHEMBL28641384 | 0.76 | HTT (0.36) | HTTTBXAS1ALDH1A1NFKB1QPCT | |
| Sulfuric Acid SCHEMBL28641383 | 0.76 | HTT (0.36) | HTTTBXAS1ALDH1A1NFKB1QPCT | |
| SCHEMBL1681806 | 0.72 | HTT (0.36) | HTTTBXAS1ALDH1A1NFKB1QPCT | |
| SCHEMBL7603750 | 0.70 | — | — | |
| Morpholine SCHEMBL28733882 | 0.69 | MEN1 (0.38) | TBXAS1NFKB1QPCTHSD17B10QPCTL | |
| Sulfuric Acid SCHEMBL28440438 | 0.69 | HTT (0.39) | HTTTBXAS1ALDH1A1NFKB1QPCT | |
| Sulfuric Acid SCHEMBL28440439 | 0.69 | HTT (0.39) | HTTTBXAS1ALDH1A1NFKB1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694512-B | Preparation method of progesterone | 浙江工商大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-112694512-A | Preparation method of progesterone | 浙江工商大学 | 2021-04-23 | — | — | CN | disclosed |