Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648950 | 1.00 | LSS (0.38) | LSSGLAEPHX2EPHX1TSHR | |
| SCHEMBL28566117 | 0.86 | LSS (0.39) | LSSSMN1; SMN2LMNAALDH1A1NAMPT | |
| SCHEMBL28334816 | 0.85 | LSS (0.37) | LSSSMN1; SMN2LMNANAMPT | |
| SCHEMBL28334814 | 0.85 | LSS (0.37) | LSSSMN1; SMN2LMNANAMPT | |
| SCHEMBL29575514 | 0.84 | PRMT5 (0.42) | EPHX2EPHX1ALDH1A1KMT2A | |
| SCHEMBL21767377 | 0.81 | NAMPT (0.37) | LSSNAMPT | |
| SCHEMBL21767375 | 0.81 | NAMPT (0.37) | LSSNAMPT | |
| SCHEMBL28559049 | 0.80 | LMNA (0.35) | LSSTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18426120 | 0.78 | KMT2A (0.42) | KMT2A | |
| SCHEMBL18426119 | 0.78 | KMT2A (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645977-A | Compounds, compositions and methods for treatment of disease | F-星治疗公司 | 2021-11-12 | — | — | CN | disclosed |