SCHEMBL28648972

SCHEMBL28648972

CCCCCC[SiH](CCCCCC)OCCOC

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.35
TSHR P16473 1/20 0.35
LPAR3 Q9UBY5 3/20 0.33
LPAR1 Q92633 2/20 0.33
LPAR2 Q9HBW0 2/20 0.33
FAAH O00519 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28642805 0.98 TSHR (0.30) THRBTSHRLPAR3LPAR1LPAR2
SCHEMBL28662868 0.91 CYP3A4 (0.31)
SCHEMBL9547135 0.84 THRB (0.40) THRBTSHRLPAR3LPAR1LPAR2
SCHEMBL19356712 0.83 THRB (0.35) THRBTSHRLPAR3LPAR1LPAR2
SCHEMBL19356770 0.80 TSHR (0.30) THRBTSHRLPAR3LPAR1LPAR2
SCHEMBL29568765 0.80 CYP3A4 (0.30)
SCHEMBL28663646 0.79 THRB (0.40) THRBTSHRLPAR3LPAR1LPAR2
Hexadecane SCHEMBL5074970 0.78 TSHR (0.57) THRBTSHRLPAR3LPAR1LPAR2
Heptane SCHEMBL16826657 0.78 TSHR (0.57) THRBTSHRLPAR3LPAR1LPAR2
Decane SCHEMBL5077906 0.78 TSHR (0.57) THRBTSHRLPAR3LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715680-B Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions 株式会社普利司通 2021-10-19 CN disclosed