Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649160 | 1.00 | KLK7 (0.38) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL28649158 | 1.00 | KLK7 (0.38) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL223309 | 0.82 | KLK7 (0.39) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL2741064 | 0.82 | KLK7 (0.39) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL223310 | 0.82 | KLK7 (0.39) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL30302061 | 0.82 | KLK7 (0.38) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL28520961 | 0.82 | YAP1 (0.39) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL28643591 | 0.82 | KLK7 (0.38) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL28643588 | 0.82 | KLK7 (0.38) | KLK7SPHK1GPR119CTSLBRD4 | |
| SCHEMBL14043466 | 0.81 | SPHK1 (0.39) | KLK7SPHK1GPR119CTSLBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113573779-A | C10-alkylene substituted 13-membered macrolides and their use | 齐卡尼治疗股份有限公司 | 2021-10-29 | — | — | CN | disclosed |