Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.70 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106961 | 0.85 | HTR2C (0.69) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL20477570 | 0.85 | EPHX2 (0.76) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL20477542 | 0.84 | EPHX2 (0.74) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL95452 | 0.84 | EPHX2 (0.74) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL14195834 | 0.83 | EPHX2 (0.74) | EPHX2NR1H4PPARGPPARANAMPT | |
| SCHEMBL3577590 | 0.83 | EPHX2 (0.73) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL27920874 | 0.83 | MAPK14 (0.74) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL23884738 | 0.82 | NPC1 (0.68) | EPHX2NR1H4PPARGHPGDALDH1A1 | |
| SCHEMBL17339262 | 0.82 | EPHX2 (0.70) | EPHX2NR1H4PPARGPPARAHTR2C | |
| SCHEMBL27931800 | 0.81 | EPHX2 (0.70) | EPHX2NR1H4PPARGPPARAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |