SCHEMBL28649356

SCHEMBL28649356

Cc1ccc(/C=C\c2ccc(Br)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.68
NFE2L2 Q16236 4/20 0.58
RAB9A P51151 2/20 0.56
CYP2C19 P33261 2/20 0.56
KDM4E B2RXH2 1/20 0.56
HPGD P15428 1/20 0.56
RELA Q04206 1/20 0.54
PTGS1 P23219 2/20 0.50
PTGS2 P35354 2/20 0.50
ALOX5 P09917 1/20 0.50
TUBB4A P04350 2/20 0.48
TUBB P07437 2/20 0.48
TUBA3C P0DPH7 2/20 0.48
TUBA1B P68363 2/20 0.48
TUBA4A P68366 2/20 0.48
TUBB4B P68371 2/20 0.48
TUBB3 Q13509 2/20 0.48
TUBB2A Q13885 2/20 0.48
TUBB8 Q3ZCM7 2/20 0.48
TUBA3E Q6PEY2 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14267407 1.00 ALDH1A1 (0.68) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL6760777 1.00 ALDH1A1 (0.68) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL2605622 1.00 ALDH1A1 (0.68) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL2622599 0.90 ALDH1A1 (0.62) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL4316553 0.87 ALDH1A1 (0.52) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL18567985 0.87 ALDH1A1 (0.52) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL14584900 0.87 ALDH1A1 (0.52) ALDH1A1NFE2L2RAB9ACYP2C19KDM4E
SCHEMBL3373054 0.86 ALDH1A1 (0.61) ALDH1A1RAB9ACYP2C19KDM4EHPGD
SCHEMBL9679607 0.86 ALDH1A1 (0.61) ALDH1A1RAB9ACYP2C19KDM4EHPGD
SCHEMBL9679616 0.86 ALDH1A1 (0.61) ALDH1A1RAB9ACYP2C19KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480396-B Method for synthesizing cis-olefin by selective semi-hydrogenation 湖南大学 2023-05-05 CN disclosed
CN-113480396-A Method for synthesizing cis-olefin by selective semi-hydrogenation 湖南大学 2021-10-08 CN disclosed