Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 6/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517043 | 0.79 | GAA (0.52) | METTOP1ENPP1KDM1AALDH1A1 | |
| SCHEMBL29645242 | 0.79 | GAA (0.52) | METTOP1ENPP1KDM1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL14871696 | 0.77 | ALDH1A1 (0.50) | METTOP1ENPP1KDM1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL31201120 | 0.77 | ALDH1A1 (0.50) | METTOP1ENPP1KDM1AALDH1A1 | |
| SCHEMBL25712 | 0.74 | MAPT (0.52) | ALDH1A1KMT2AGAARAB9AMAPT | |
| SCHEMBL28150996 | 0.73 | MAPT (0.46) | METTOP1KDM1AALDH1A1KMT2A | |
| SCHEMBL5987759 | 0.72 | KMT2A (0.56) | METTOP1ALDH1A1KMT2AGAA | |
| SCHEMBL5143917 | 0.70 | TOP1 (0.43) | METTOP1ENPP1KDM1AALDH1A1 | |
| SCHEMBL655231 | 0.70 | MYC (0.38) | ALDH1A1KMT2AGAARAB9AMAPT | |
| Pyrimidine SCHEMBL29066608 | 0.70 | TOP1 (0.46) | METTOP1KDM1AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117495-B | Spirofluorene ring compound, use thereof, and organic electroluminescent device using the same | 北京鼎材科技有限公司 | 2021-11-19 | — | — | CN | claimed |