Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 15/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638744 | 0.90 | GNRHR (0.45) | GNRHRCYP3A4CTSA | |
| SCHEMBL21900224 | 0.89 | GNRHR (0.43) | GNRHRCYP3A4CTSA | |
| SCHEMBL19873886 | 0.84 | GNRHR (0.45) | GNRHRCYP3A4 | |
| SCHEMBL30178655 | 0.84 | GNRHR (0.45) | GNRHRCYP3A4 | |
| SCHEMBL19873738 | 0.83 | GNRHR (0.45) | GNRHRCYP3A4 | |
| SCHEMBL30178407 | 0.83 | GNRHR (0.44) | GNRHRCYP3A4CTSA | |
| SCHEMBL17870751 | 0.83 | GNRHR (0.44) | GNRHRCYP3A4CTSA | |
| SCHEMBL19873721 | 0.81 | GNRHR (0.47) | GNRHRCYP3A4KDM4E | |
| SCHEMBL28638669 | 0.80 | GNRHR (0.39) | GNRHRCYP3A4P2RX3CTSA | |
| SCHEMBL21900242 | 0.78 | GNRHR (0.37) | GNRHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |