Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 17/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178407 | 1.00 | GNRHR (0.44) | GNRHRCYP3A4MAPTCTSA | |
| SCHEMBL19873721 | 0.94 | GNRHR (0.47) | GNRHRCYP3A4 | |
| SCHEMBL21900224 | 0.89 | GNRHR (0.43) | GNRHRCYP3A4CTSA | |
| SCHEMBL28638744 | 0.89 | GNRHR (0.45) | GNRHRCYP3A4CTSA | |
| SCHEMBL19873738 | 0.84 | GNRHR (0.45) | GNRHRCYP3A4 | |
| SCHEMBL19873886 | 0.83 | GNRHR (0.45) | GNRHRCYP3A4 | |
| SCHEMBL28649424 | 0.83 | GNRHR (0.45) | GNRHRCYP3A4CTSA | |
| SCHEMBL30178655 | 0.83 | GNRHR (0.45) | GNRHRCYP3A4 | |
| SCHEMBL30178393 | 0.82 | GNRHR (0.42) | GNRHRCYP3A4MAPT | |
| SCHEMBL21900242 | 0.78 | GNRHR (0.37) | GNRHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| EP-3708566-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |