Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GLB1 | P16278 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28649473 | 1.00 | MAN1B1 (0.55) | MAN1B1GBA1FUCA1GLAGAA | |
| Trifluoroacetic Acid SCHEMBL48017 | 0.87 | MAN1B1 (0.36) | MAN1B1GBA1FUCA1GLAGAA | |
| Trifluoroacetic Acid SCHEMBL30135510 | 0.85 | FUCA1 (0.48) | MAN1B1GBA1FUCA1GLAGAA | |
| Trifluoroacetic Acid SCHEMBL29716678 | 0.85 | MAN1B1 (0.39) | MAN1B1SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL2895465 | 0.82 | CHRNA7 (0.36) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL4831016 | 0.82 | CCR5 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL928724 | 0.82 | CCR5 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL23275364 | 0.82 | MAN1B1 (0.36) | MAN1B1GBA1FUCA1GLAGAA | |
| Trifluoroacetic Acid SCHEMBL31309456 | 0.81 | HPSE (0.36) | MAN1B1GBA1FUCA1GLAGAA | |
| Trifluoroacetic Acid SCHEMBL9597073 | 0.80 | MAN1B1 (0.34) | MAN1B1GBA1FUCA1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912617-A | Substituted tricycles and methods of use | 艾伯维公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108349930-B | Substituted tricycles and methods of use | 艾伯维公司 | 2021-10-29 | — | — | CN | disclosed |