Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529291 | 0.91 | HTT (0.60) | KEAP1NFE2L2HTTALDH1A1ITGB3 | |
| SCHEMBL12195307 | 0.89 | HTT (0.61) | KEAP1NFE2L2HTTALDH1A1ITGB3 | |
| SCHEMBL20389719 | 0.88 | HTT (0.60) | KEAP1NFE2L2HTTALDH1A1ITGB3 | |
| SCHEMBL13599671 | 0.88 | HTT (0.56) | KEAP1NFE2L2HTTALDH1A1LMNA | |
| SCHEMBL30750669 | 0.87 | HTT (0.59) | KEAP1NFE2L2HTTALDH1A1ITGB3 | |
| SCHEMBL7159219 | 0.86 | LMNA (0.63) | KEAP1NFE2L2HTTALDH1A1LMNA | |
| SCHEMBL12195303 | 0.86 | HTT (0.52) | KEAP1NFE2L2HTTALDH1A1ITGB3 | |
| SCHEMBL13737251 | 0.86 | HTT (0.60) | KEAP1NFE2L2HTTALDH1A1ITGB3 | |
| SCHEMBL5108553 | 0.85 | HTT (0.56) | KEAP1NFE2L2HTTALDH1A1LMNA | |
| SCHEMBL31596983 | 0.85 | HTT (0.59) | KEAP1NFE2L2HTTALDH1A1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |