Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.47 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31314618 | 1.00 | NNMT (0.55) | NNMTSMN1; SMN2P4HTMP4HA1MIF | |
| SCHEMBL978974 | 0.84 | NNMT (0.63) | NNMTSMN1; SMN2P4HTMP4HA1MIF | |
| Hydrochloric Acid SCHEMBL6485765 | 0.82 | NNMT (0.61) | NNMTSMN1; SMN2P4HTMP4HA1MIF | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL2275968 | 0.82 | P4HTM (0.52) | P4HTMP4HA1MIFKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7702795 | 0.82 | NNMT (0.61) | NNMTSMN1; SMN2P4HTMP4HA1MIF | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL25439990 | 0.82 | P4HTM (0.53) | P4HTMP4HA1MIFKDM4EL3MBTL1 | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL9367783 | 0.82 | P4HTM (0.52) | P4HTMP4HA1MIFKDM4EL3MBTL1 | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL9341722 | 0.82 | P4HTM (0.52) | P4HTMP4HA1MIFKDM4EL3MBTL1 | |
| SCHEMBL1978610 | 0.80 | P4HTM (0.73) | NNMTSMN1; SMN2P4HTMP4HA1MIF | |
| SCHEMBL6476554 | 0.78 | NNMT (0.57) | NNMTSMN1; SMN2P4HTMP4HA1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354931-A | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113563244-A | Substituted aza five-membered ring compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-10-29 | — | — | CN | disclosed |