Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.68 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28664423 | 1.00 | DNM1 (0.68) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL27990634 | 0.95 | DNM1 (0.76) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL27990633 | 0.95 | DNM1 (0.76) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL27990972 | 0.95 | DNM1 (0.76) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL27990986 | 0.95 | DNM1 (0.76) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL27990911 | 0.95 | DNM1 (0.76) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL28815241 | 0.95 | DNM1 (0.76) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Tetrahexylammonium SCHEMBL2275856 | 0.93 | SLC22A1 (0.72) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL20985063 | 0.93 | SLC22A1 (0.72) | DNM1SLC22A1ALDH1A1TSHRTP53 | |
| Bicarbonate SCHEMBL11432946 | 0.93 | SLC22A1 (0.72) | DNM1SLC22A1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109777639-B | Preparation for disinfecting and cleaning hard surface of air conditioner and general objects and preparation method thereof | 江苏今日卫生用品有限公司 | 2021-11-16 | — | — | CN | disclosed |