Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858671 | 0.88 | BRD4 (0.43) | CASRNR1I2 | |
| SCHEMBL3418288 | 0.82 | CASR (0.66) | CASRNR1I2 | |
| SCHEMBL2839040 | 0.78 | CASR (0.63) | CASRNR1I2 | |
| SCHEMBL3418275 | 0.78 | NR1I2 (0.51) | CASRNR1I2 | |
| SCHEMBL3417598 | 0.75 | CASR (0.60) | CASRNR1I2 | |
| SCHEMBL2840722 | 0.74 | CASR (0.73) | CASRNR1I2 | |
| SCHEMBL3418557 | 0.74 | NR1I2 (0.66) | CASRNR1I2 | |
| Hydrochloric Acid SCHEMBL2835851 | 0.74 | CASR (0.72) | CASRNR1I2 | |
| SCHEMBL3421350 | 0.73 | NR1I2 (0.63) | CASRNR1I2 | |
| SCHEMBL2835550 | 0.73 | CASR (0.61) | CASRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039913-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | claimed |
| WO-2010039913-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039913-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |