Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18915103 | 0.85 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| SCHEMBL31222429 | 0.78 | CYP2A6 (0.50) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| SCHEMBL24656655 | 0.78 | CYP2A6 (0.50) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| SCHEMBL2906916 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CYP1A2ERBB2FYNMAOA | |
| SCHEMBL31504059 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| SCHEMBL4070428 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| Thiophene SCHEMBL27865842 | 0.73 | CYP1A2 (0.38) | ALDH1A1CYP1A2ERBB2FYNMAOA | |
| SCHEMBL662611 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| SCHEMBL31108073 | 0.72 | HSD17B10 (0.60) | ALDH1A1CYP1A2CYP2A6ERBB2FYN | |
| SCHEMBL21313671 | 0.72 | CYP1A2 (0.48) | ALDH1A1CYP1A2CYP2A6ERBB2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117511-B | Spirofluorene ring compound, use thereof, and organic electroluminescent device using the same | 北京鼎材科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108117548-B | Spirofluorene compound, application thereof, thermal activation delayed fluorescence material and organic electroluminescent device using spirofluorene compound | 北京鼎材科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-108117495-B | Spirofluorene ring compound, use thereof, and organic electroluminescent device using the same | 北京鼎材科技有限公司 | 2021-11-19 | — | — | CN | disclosed |