SCHEMBL2865008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2872869	0.89	ROCK2 (0.50)	CSNK1DNPC1RAB9AMEN1ALDH1A1
	SCHEMBL2870025	0.88	ROCK2 (0.44)	CSNK1DTTKMAPK3MAPK1EGLN1
	SCHEMBL2860995	0.81	HPGD (0.47)	KDM4ERAB9AALDH1A1MAPK1HPGD
	SCHEMBL4327029	0.80	HTT (0.47)	KDM4EALDH1A1MAPK3MAPK1HPGD
	SCHEMBL4328099	0.80	MAPK1 (0.40)	CSNK1DNPC1RAB9ATTKALDH1A1
	SCHEMBL4331515	0.77	TTK (0.49)	KDM4ENPC1RAB9ATTKALDH1A1
	SCHEMBL4334934	0.77	HPGD (0.56)	NPC1RAB9AMEN1ALDH1A1KMT2A
	SCHEMBL4334043	0.76	PTGDR2 (0.42)	CSNK1DKDM4ENPC1RAB9AMEN1
	SCHEMBL4341443	0.75	TP53 (0.41)	CSNK1DKDM4ENPC1RAB9AMEN1
	SCHEMBL2862711	0.75	HDAC3 (0.47)	ITKROCK1ROCK2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.