Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411450 | 0.92 | CTNNB1 (0.66) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| SCHEMBL8674779 | 0.90 | CTNNB1 (0.56) | CTNNB1HTTALDH1A1 | |
| SCHEMBL9252102 | 0.89 | CTNNB1 (0.67) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| SCHEMBL1798 | 0.88 | CTNNB1 (0.71) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| SCHEMBL11875755 | 0.86 | CTNNB1 (0.69) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| Bicarbonate SCHEMBL21517637 | 0.86 | CTNNB1 (0.69) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| SCHEMBL8496446 | 0.86 | CTNNB1 (0.69) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| Bicarbonate SCHEMBL236889 | 0.86 | CTNNB1 (0.69) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| SCHEMBL4129945 | 0.86 | CTNNB1 (0.69) | CTNNB1HTTALDH1A1HPGDKDM4E | |
| SCHEMBL11407865 | 0.86 | CTNNB1 (0.69) | CTNNB1HTTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546106-A | Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof | 宁夏大学 | 2024-08-27 | — | — | CN | disclosed |
| CN-117164517-A | Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof | 西北农林科技大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-102083836-B | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX INC | 2015-01-28 | — | — | CN | disclosed |
| US-20130295261-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-8420145-B2 | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| CN-102083836-A | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX INC | 2011-06-01 | — | — | CN | disclosed |
| EP-2254891-A2 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009111447-A2 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. | 2009-09-03 | — | — | US | disclosed |
| US-7582664-B2 | Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2009-09-01 | — | — | US | disclosed |
| US-5216178-A | Contacting with alkaline earth metal and lower alkanol | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-01 | — | — | US | disclosed |
| US-5140027-A | Antidepressants, analgesics and anticonvulsants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-08-18 | — | — | US | disclosed |
| US-4943571-A | ANALGESICS, ANTICONVULSANTS, ANTIDEPRESSANTS | HOECHST-ROUSSEL PHAMRACEUTICALS INC. (US) | 1990-07-24 | — | — | US | disclosed |
| US-4837227-A | ANALGESICS, ANTIDEPRESSANTS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0016261-B1 | SPIRO(DIBENZ(B,F)OXEPIN-PIPERIDINES) AND METHODS OF PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |
| EP-0002508-B1 | AMINOALKYLTHIODIBENZOXEPINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-31 | — | — | EP | disclosed |
| EP-0016261-A1 | Spiro(dibenz(b,f)oxepin-piperidines) and methods of preparing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-10-01 | — | — | EP | disclosed |
| US-4198418-A | ANALGESICS, TRANQUILIZERS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198417-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| EP-0002508-A1 | Aminoalkylthiodibenzoxepines, their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | TAS2R10, TAS2R41, TAS2R30 | CTNNB1 4794/4885HTT 2197/4885SCN8A 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.