SCHEMBL2865013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864778	0.83	ITK (0.54)	LRRK2ITKMAP2K4
	SCHEMBL2859279	0.81	ITK (0.64)	LRRK2ITK
	SCHEMBL2466587	0.80	PIM1 (0.56)	LRRK2PIM1PDPK1MAP2K4MAPK1
	SCHEMBL2860003	0.80	ITK (0.54)	LRRK2ITKMAPK1
	SCHEMBL17829665	0.79	AURKA (0.60)	LRRK2PIM1PDPK1MAP2K4MAPK1
	SCHEMBL17829688	0.78	PDPK1 (0.57)	LRRK2PIM1PDPK1MAP2K4MAPK1
	SCHEMBL2868413	0.77	LRRK2 (0.58)	LRRK2ITK
	SCHEMBL699881	0.76	PIM1 (0.52)	LRRK2PIM1PDPK1MAP2K4MAPK1
	SCHEMBL2860093	0.76	MAP2K4 (0.71)	LRRK2PIM1PDPK1MAP2K4MAPK1
	SCHEMBL5373058	0.76	MAP2K4 (0.63)	LRRK2PIM1ITKMAP2K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.