SCHEMBL28650613

SCHEMBL28650613

O=S(=O)(O)c1cc(Cl)c(O)c(Cl)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.44
TSHR P16473 4/20 0.44
HPGD P15428 3/20 0.44
MAPK1 P28482 2/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ALDH1A1 P00352 2/20 0.39
CASP1 P29466 2/20 0.39
CASP7 P55210 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
NSD2 O96028 1/20 0.38
MMP14 P50281 1/20 0.38
CASP6 P55212 1/20 0.38
TTR P02766 2/20 0.37
CYP3A4 P08684 2/20 0.37
RECQL P46063 2/20 0.37
F2 P00734 2/20 0.37
PRSS1 P07477 2/20 0.37
PRSS2 P07478 2/20 0.37
PRSS3 P35030 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9150239 0.89 HSD17B10 (0.42) HSD17B10TSHRHPGDMAPK1CA1
SCHEMBL31251954 0.83 HSD17B10 (0.48) HSD17B10TSHRHPGDMAPK1CA1
SCHEMBL27639479 0.83 HSD17B10 (0.48) HSD17B10TSHRHPGDMAPK1CA1
SCHEMBL9551117 0.82 HSD17B10 (0.39) HSD17B10TSHRHPGDCA1CA2
SCHEMBL8442650 0.81 HPGD (0.35) HSD17B10TSHRHPGDMAPK1CA1
SCHEMBL5318762 0.81 CA1 (0.41) HSD17B10TSHRHPGDMAPK1CA1
SCHEMBL8437999 0.79 FABP3 (0.38) HSD17B10TSHRHPGDCA1CA2
SCHEMBL29364988 0.78 CA1 (0.68) HSD17B10TSHRCA1CA2ALDH1A1
SCHEMBL397094 0.78 CA1 (0.68) HSD17B10TSHRCA1CA2ALDH1A1
SCHEMBL8504453 0.78 CA1 (0.43) HSD17B10TSHRHPGDMAPK1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114152737-B Urine galactose detection kit 广东阳光生物科技有限公司 2024-06-07 CN disclosed
CN-117887791-A Giant salamander bone peptide extract, preparation method and application thereof 清华大学深圳国际研究生院 2024-04-16 CN disclosed
CN-116640655-B Portable urine galactose detection kit stored at normal temperature, reaction liquid and preparation method thereof 北京中生金域诊断技术股份有限公司 2024-03-29 CN disclosed
CN-116640655-A Portable urine galactose detection kit stored at normal temperature, reaction liquid and preparation method thereof 北京中生金域诊断技术股份有限公司 2023-08-25 CN disclosed
CN-106645132-B Test paper for detecting lactose content in sample and preparation method of test paper 厦门信道生物技术有限公司 2023-07-18 CN disclosed
CN-217786913-U Kit for detection 江苏鱼跃凯立特生物科技有限公司 2022-11-11 CN disclosed
CN-115240865-A Detection information processing method and system 深圳傲威网络有限公司 2022-10-25 CN disclosed
CN-114678093-A Detection information processing method and system 深圳傲威网络有限公司 2022-06-28 CN disclosed
CN-114073754-A Giant salamander bone meal extract, preparation method and application thereof 清华大学 2022-02-22 CN disclosed
CN-113647947-A AI intelligence uric acid detects, diagnostic medical robot of analysis 深圳百岁欢智能科技有限公司 2021-11-16 CN disclosed