Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650613 | 0.89 | HSD17B10 (0.44) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL842154 | 0.86 | PGAM1 (0.42) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL843141 | 0.84 | PGAM1 (0.41) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL1224928 | 0.81 | PGAM1 (0.53) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL31251954 | 0.79 | HSD17B10 (0.48) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL27639479 | 0.79 | HSD17B10 (0.48) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL28145555 | 0.79 | PGAM1 (0.52) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL28146678 | 0.79 | PGAM1 (0.52) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL11100105 | 0.79 | CA1 (0.43) | HSD17B10CASP1ALDH1A1CASP7TDP1 | |
| SCHEMBL9551117 | 0.79 | HSD17B10 (0.39) | HSD17B10CASP1ALDH1A1CASP7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410083-A | Synthesis of diaminoresorcinal from resorcinol | THE DOW CHEMICAL COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5371291-A | Blocking, halogenating, removal the blocking, concurrent nitrating and hydrogenating | THE DOW CHEMICAL COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0146923-B1 | PREPARATION OF HALOGENATED PHENOLS | FIDIA S.p.A. (IT) | 1991-07-10 | — | — | EP | disclosed |
| US-4704469-A | Preparation of halogenated phenols | FIDIA S.P.A. (IT) | 1987-11-03 | — | — | US | disclosed |
| EP-0146923-A1 | Preparation of halogenated phenols | FIDIA S.p.A. (IT) | 1985-07-03 | — | — | EP | disclosed |