Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650013 | 0.84 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL19030551 | 0.70 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL19030240 | 0.70 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL28655169 | 0.68 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL19046422 | 0.63 | IRAK4 (0.44) | IRAK4 | |
| SCHEMBL19030619 | 0.62 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL19046097 | 0.60 | IRAK4 (0.52) | IRAK4 | |
| SCHEMBL19030289 | 0.60 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL1740813 | 0.58 | HTR1F (0.40) | — | |
| SCHEMBL19030736 | 0.56 | IRAK4 (0.42) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473498-B | Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2021-11-02 | — | — | CN | disclosed |