Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650955 | 1.00 | GPR119 (0.41) | GPR119CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL31488395 | 1.00 | GPR119 (0.41) | GPR119CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL720548 | 0.90 | CHRM2 (0.49) | GPR119CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL10052777 | 0.90 | CHRM2 (0.49) | GPR119CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL720547 | 0.90 | CHRM2 (0.49) | GPR119CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL22325318 | 0.84 | KCNH2 (0.34) | LMNAKMT2A | |
| SCHEMBL30186325 | 0.81 | GPR119 (0.33) | GPR119KMT2AKCNK3KCNK9 | |
| SCHEMBL23545074 | 0.79 | GPR119 (0.47) | GPR119LMNAKMT2AKCNK3KCNK9 | |
| SCHEMBL20936937 | 0.79 | GPR119 (0.47) | GPR119LMNAKMT2AKCNK3KCNK9 | |
| SCHEMBL20936756 | 0.79 | GPR119 (0.47) | GPR119LMNAKMT2AKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113661162-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2021-11-16 | — | — | CN | disclosed |