Histidine

Histidine

SCHEMBL28650960

CSCCC(N)C(=O)O.NC(Cc1c[nH]cn1)C(=O)O.[Cu]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
SLC7A5 Q01650 1/20 0.40
CYP1A2 P05177 1/20 0.36
BHMT Q93088 4/20 0.35
BHMT2 Q9H2M3 1/20 0.35
GRIA1 P42261 2/20 0.35
GRIA2 P42262 2/20 0.35
GRIA3 P42263 2/20 0.35
GRIA4 P48058 2/20 0.35
CTSC P53634 2/20 0.33
NOS2 P35228 2/20 0.33
RNPEP Q9H4A4 1/20 0.33
ARG1 P05089 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL342892 0.99 CYP3A4 (0.40) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL27681989 0.99 CYP3A4 (0.40) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL342891 0.99 CYP3A4 (0.40) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL27729896 0.94 CYP3A4 (0.37) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL28888007 0.94 CYP3A4 (0.37) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL23362032 0.93 CYP1A2 (0.42) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL28942432 0.93 FNTA (0.38) CYP3A4SLC7A5
Histidine SCHEMBL23362634 0.93 BHMT (0.39) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL6805147 0.93 SLC7A5 (0.38) CYP3A4SLC7A5CYP1A2BHMTBHMT2
Histidine SCHEMBL1884290 0.93 SLC7A5 (0.38) CYP3A4SLC7A5CYP1A2BHMTBHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113713860-B Catalytic luminescent copper cluster nanoenzyme and preparation method and application thereof 东南大学 2023-02-28 CN disclosed
CN-113713860-A Catalytic luminescent copper cluster nanoenzyme and preparation method and application thereof 东南大学 2021-11-30 CN disclosed