Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664223 | 0.91 | KRAS (0.56) | KRAS | |
| SCHEMBL28661182 | 0.90 | KRAS (0.41) | KRAS | |
| SCHEMBL28661230 | 0.89 | KRAS (0.45) | KRAS | |
| SCHEMBL29693085 | 0.88 | KRAS (0.44) | KRAS | |
| SCHEMBL28928620 | 0.86 | KRAS (0.45) | KRAS | |
| SCHEMBL28676533 | 0.85 | KRAS (0.44) | KRAS | |
| SCHEMBL28656532 | 0.83 | KRAS (0.54) | KRAS | |
| SCHEMBL28671533 | 0.82 | KRAS (0.53) | KRAS | |
| SCHEMBL28658835 | 0.81 | KRAS (0.48) | KRAS | |
| SCHEMBL28654351 | 0.81 | KRAS (0.55) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-A | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2021-10-15 | — | — | CN | disclosed |