Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11889380 | 1.00 | DPP8 (0.48) | DPP8DPP9DPP7ACHEBACE1 | |
| SCHEMBL11889561 | 1.00 | DPP8 (0.48) | DPP8DPP9DPP7ACHEBACE1 | |
| SCHEMBL11889448 | 0.90 | DRD4 (0.49) | DPP8DPP9DPP7ACHEBACE1 | |
| SCHEMBL11889388 | 0.90 | DRD4 (0.49) | DPP8DPP9DPP7ACHEBACE1 | |
| SCHEMBL20766109 | 0.87 | BCHE (0.46) | ACHEBACE1BCHEGRIN2BMEN1 | |
| SCHEMBL10320157 | 0.82 | JAK1 (0.54) | ACHEKMT2A | |
| SCHEMBL22435955 | 0.82 | JAK1 (0.54) | ACHEKMT2A | |
| SCHEMBL4875893 | 0.82 | JAK1 (0.54) | ACHEKMT2A | |
| SCHEMBL10449417 | 0.82 | JAK1 (0.54) | ACHEKMT2A | |
| SCHEMBL14699811 | 0.80 | ACHE (0.49) | ACHEBACE1BCHEFYNGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631557-A | JAK kinase inhibitor, preparation method thereof and application thereof in medical field | 上海华汇拓医药科技有限公司 | 2021-11-09 | — | — | CN | disclosed |