Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926766 | 0.82 | DDB1 (0.45) | KMT2ALMNADDB1CRBN | |
| SCHEMBL28972414 | 0.71 | CYP19A1 (0.56) | MMP13SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL2829814 | 0.66 | TDP1 (0.54) | MMP13SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL17583744 | 0.66 | KMT2A (0.66) | MMP13SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL24516525 | 0.65 | SLC6A4 (0.46) | MMP13SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL680920 | 0.65 | DDB1 (0.47) | KMT2ADDB1CRBN | |
| SCHEMBL30479180 | 0.65 | MAPT (0.46) | MMP13SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL4137088 | 0.65 | MAPT (0.46) | MMP13SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL7359606 | 0.65 | MMP13 (0.39) | MMP13SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4286233 | 0.64 | MAPT (0.44) | MMP13SLC6A2SLC6A4SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |