Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664532 | 0.85 | BCL9 (0.57) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL7981288 | 0.80 | BCL9 (0.64) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL24345826 | 0.80 | ALDH1A1 (0.50) | MGLLSMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL4988861 | 0.77 | GAA (0.57) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL1400174 | 0.76 | BCL9 (0.80) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL1916980 | 0.75 | BCL9 (0.78) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL135634 | 0.75 | BCL9 (0.78) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL22531036 | 0.75 | BCL9 (0.78) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL7754480 | 0.75 | BCL9 (0.78) | MGLLBCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL13184389 | 0.75 | BCL9 (0.78) | MGLLBCL9CTNNB1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156800-B | Synthesis method of pyrano [3,2-b ] indole-2-ketone compound | 中国药科大学 | 2021-11-26 | — | — | CN | disclosed |