Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678438 | 0.86 | CRBN (0.66) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL28649711 | 0.85 | CRBN (0.53) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL21751116 | 0.84 | CRBN (0.64) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL4779765 | 0.83 | CRBN (0.55) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL28672625 | 0.78 | CRBN (0.51) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL28668395 | 0.78 | CRBN (0.53) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL21751086 | 0.78 | CRBN (0.69) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL30822369 | 0.76 | CRBN (0.58) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL25237018 | 0.75 | CRBN (0.57) | CRBNDDB1IKZF3 | |
| SCHEMBL21751096 | 0.75 | CRBN (0.54) | CRBNDDB1BRD4IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480520-B | Isoquinoline-1, 3(2H, 4H) -diketone derivative and application thereof | 吉林大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113480520-A | Isoquinoline-1, 3(2H,4H) -diketone derivative and application thereof | 吉林大学 | 2021-10-08 | — | — | CN | disclosed |