Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649711 | 0.87 | CRBN (0.53) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL21751086 | 0.86 | CRBN (0.69) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL13678438 | 0.85 | CRBN (0.66) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL21751116 | 0.83 | CRBN (0.64) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL28653719 | 0.83 | CRBN (0.55) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL15875012 | 0.82 | CRBN (0.51) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL30919440 | 0.82 | CRBN (0.51) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL4778581 | 0.82 | CRBN (0.73) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL21767269 | 0.79 | CRBN (0.47) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL4778728 | 0.79 | CRBN (0.74) | CRBNDDB1BRD4IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | claimed |
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | disclosed |