Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19044618 | 0.91 | ALDH1A1 (0.45) | IRAK4 | |
| SCHEMBL19030128 | 0.89 | IRAK4 (0.52) | IRAK4 | |
| SCHEMBL19030096 | 0.87 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL19029985 | 0.86 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL19030045 | 0.86 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL19030527 | 0.86 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL20594277 | 0.83 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL19030543 | 0.83 | IRAK4 (0.52) | IRAK4 | |
| SCHEMBL19030950 | 0.83 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19030071 | 0.83 | IRAK4 (0.51) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473498-B | Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2021-11-02 | — | — | CN | disclosed |