Phthalic Acid

Phthalic Acid

SCHEMBL28654022

CC(O)C(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 known ✓ Q9BY41 1/20 0.54
ALDH1A1 P00352 4/20 0.67
ALOX15 P16050 1/20 0.67
MAPT P10636 1/20 0.54
TP53 P04637 1/20 0.52
AKR1C3 P42330 2/20 0.52
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
HMGB1 P09429 1/20 0.50
CA6 P23280 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CA14 Q9ULX7 1/20 0.50
LMNA P02545 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL28071671 0.98 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTHDAC8TP53
Phthalic Acid SCHEMBL28056982 0.96 ALDH1A1 (0.61) ALDH1A1ALOX15MAPTHDAC8TP53
Phthalic Acid SCHEMBL9719105 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL27774192 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL29165245 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28071670 0.88 ALDH1A1 (0.52) ALDH1A1ALOX15MAPTHDAC8TP53
Phthalic Acid SCHEMBL28006650 0.88 ALDH1A1 (0.70) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28233584 0.88 ALDH1A1 (0.70) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28418540 0.87 ALDH1A1 (0.78) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Salicylic Acid SCHEMBL31251472 0.87 ALDH1A1 (0.72) ALDH1A1ALOX15MAPTHDAC8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113621182-A Preparation process and equipment of cellulose lactate phthalate sustained-release material 山东友成生物科技有限公司 2021-11-09 CN disclosed
CN-113621182-A Preparation process and equipment of cellulose lactate phthalate sustained-release material 山东友成生物科技有限公司 2021-11-09 CN disclosed