Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421623 | 0.64 | CRBN (0.32) | CRBNMAP3K14 | |
| SCHEMBL3741832 | 0.62 | CREBBP (0.40) | CRBNBRD4CREBBPEP300 | |
| SCHEMBL1600759 | 0.62 | CRBN (0.30) | CRBN | |
| SCHEMBL24403152 | 0.62 | CRBN (0.30) | CRBN | |
| SCHEMBL14492201 | 0.61 | MAP1LC3B (0.50) | CRBNBRD4CREBBP | |
| SCHEMBL6090122 | 0.60 | CRBN (0.33) | CRBN | |
| SCHEMBL3029983 | 0.59 | HTR2C (0.52) | CRBNBRD4CREBBP | |
| SCHEMBL19671600 | 0.59 | — | — | |
| SCHEMBL23605039 | 0.58 | — | — | |
| SCHEMBL23437848 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963851-B | Fused bicyclic pyridine compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-11-30 | — | — | CN | disclosed |