Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28667044 | 1.00 | POLB (0.45) | POLBFFAR4PKMKMT2AHTT | |
| SCHEMBL28667043 | 1.00 | POLB (0.45) | POLBFFAR4PKMKMT2AHTT | |
| SCHEMBL28668105 | 1.00 | POLB (0.45) | POLBFFAR4PKMKMT2AHTT | |
| SCHEMBL28928279 | 1.00 | POLB (0.45) | POLBFFAR4PKMKMT2AHTT | |
| SCHEMBL28654487 | 1.00 | POLB (0.45) | POLBFFAR4PKMKMT2AHTT | |
| SCHEMBL28663235 | 0.90 | POLB (0.41) | POLBPKMKMT2AHTTHSD11B1 | |
| SCHEMBL28663234 | 0.90 | POLB (0.41) | POLBPKMKMT2AHTTHSD11B1 | |
| SCHEMBL28667112 | 0.90 | POLB (0.41) | POLBPKMKMT2AHTTHSD11B1 | |
| SCHEMBL28667113 | 0.90 | POLB (0.41) | POLBPKMKMT2AHTTHSD11B1 | |
| SCHEMBL28667096 | 0.89 | ALDH1A1 (0.44) | POLBKMT2AHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912617-A | Substituted tricycles and methods of use | 艾伯维公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108349930-B | Substituted tricycles and methods of use | 艾伯维公司 | 2021-10-29 | — | — | CN | disclosed |