Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867701 | 0.81 | SRD5A2 (0.53) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL13236269 | 0.81 | MAPT (0.70) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL2868771 | 0.79 | SRD5A2 (0.51) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL3105349 | 0.79 | SRD5A2 (0.86) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL29709873 | 0.79 | SRD5A2 (0.86) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL31069845 | 0.79 | SRD5A2 (0.86) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL2864393 | 0.78 | SRD5A2 (0.50) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL28119578 | 0.77 | SRD5A2 (0.83) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL30912172 | 0.74 | SMN1; SMN2 (0.64) | SRD5A2CYP1A2HTR2CHTR2BADRA2A | |
| SCHEMBL5016641 | 0.74 | SMN1; SMN2 (0.64) | SRD5A2CYP1A2HTR2CHTR2BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834204-B2 | Fluorene derivative, transition metal compound, catalyst for olefin polymerization, and process for producing olefin polymer | MITSUI CHEMICALS, INC. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20090253876-A1 | Fluorene Derivative, Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | MITSUI CHEMICALS, INC. | 2009-10-08 | — | — | US | disclosed |
| EP-1900715-A1 | FLUORENE DERIVATIVE, TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253876-A1 | Fluorene Derivative, Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | AFF4, OR10J3, DRD1 | SRD5A2 465/4885CYP1A2 666/4885HTR2C 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.