Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18582934 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL30912172 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL5058433 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL29924230 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL3280539 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL5357317 | 0.91 | RAB9A (0.55) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL2720506 | 0.88 | ALDH1A1 (0.70) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| Fluorene SCHEMBL8180 | 0.88 | MAOA (0.68) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| Fluorene SCHEMBL31388525 | 0.88 | MAOA (0.68) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| Fluorene SCHEMBL29478468 | 0.88 | MAOA (0.68) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9461249-B2 | Compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | TYR, DDT, PAH | SMN1; SMN2 1453/4885NPC1 1783/4885MAPT 915/4885 |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | TYR, TOE1, GPX1 | SMN1; SMN2 2671/4885NPC1 2095/4885MAPT 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.