SCHEMBL28654789

SCHEMBL28654789

CNC1CCC(OC(N)=O)CC1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
EPHX1 P07099 2/20 0.34
KCNA3 P22001 1/20 0.32
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28718116 1.00 ATM (0.41) ATMEPHX1KCNA3ALOX15
SCHEMBL425737 0.82
SCHEMBL14984908 0.81 NPY5R (0.38) EPHX1
SCHEMBL38659036 0.81 ATM (0.42) ATM
SCHEMBL25766872 0.81 NPY5R (0.38) EPHX1
SCHEMBL22418641 0.81 ATM (0.42) ATM
SCHEMBL28439266 0.79
Water SCHEMBL8681204 0.79
Hydrochloric Acid SCHEMBL11162708 0.79
Hydrochloric Acid SCHEMBL28433142 0.79 ATM (0.37) ATMEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490499-A Modulators of MYC family protooncogene proteins 纳罗医疗公司 2023-07-25 CN disclosed
CN-114980976-A Covalent RAS inhibitors and uses thereof 锐新医药公司 2022-08-30 CN disclosed
CN-113710663-A Modulators of MYC family proto-oncogene proteins 纳罗医疗公司 2021-11-26 CN disclosed