SCHEMBL22418641

SCHEMBL22418641

CNC1CC(OC(N)=O)C1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38659036 1.00 ATM (0.42) ATM
SCHEMBL28654789 0.81 ATM (0.41) ATM
SCHEMBL28718116 0.81 ATM (0.41) ATM
SCHEMBL24922165 0.80 CHRM2 (0.43)
SCHEMBL23573224 0.76 ATM (0.38) ATM
SCHEMBL17295619 0.75
SCHEMBL28669754 0.73 ATM (0.45) ATM
SCHEMBL12163071 0.72 BTK (0.49) ATM
SCHEMBL28317785 0.72 DPP4 (0.40)
SCHEMBL28908080 0.72 POLB (0.44) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631557-B JAK kinase inhibitor, preparation method thereof and application thereof in medicine field 上海华汇拓医药科技有限公司 2024-03-15 CN disclosed
CN-110194770-B Peptidyl arginine deiminase inhibitors and uses thereof 药捷安康(南京)科技股份有限公司 2022-08-09 CN disclosed
CN-113631557-A JAK kinase inhibitor, preparation method thereof and application thereof in medical field 上海华汇拓医药科技有限公司 2021-11-09 CN disclosed
WO-2020182159-A1 JAK KINASE INHIBITOR, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF IN FIELD OF MEDICINE 上海华汇拓医药科技有限公司 2020-09-17 WO disclosed