Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28201319 | 0.90 | — | — | |
| Acetic Acid SCHEMBL12474237 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAGABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL28858092 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAGABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL3336394 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAGABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL8817349 | 0.88 | — | — | |
| Acetic Acid SCHEMBL6150069 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAGABRPGABRDGABRA1 | |
| Carbamic Acid SCHEMBL11588805 | 0.88 | — | — | |
| Acetic Acid SCHEMBL21227 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAGABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL9406859 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAGABRPGABRDGABRA1 | |
| SCHEMBL10903093 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNAALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685383-B | Preparation method of dexrazoxane | 四川汇宇制药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-113636980-B | Preparation method of dexrazoxane | 北京泰德制药股份有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-110804022-B | Preparation method of dexrazoxane | 扬子江药业集团有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114685383-A | Preparation method of dexrazoxane | 四川汇宇制药股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113636980-A | Preparation method of dexrazoxane | 北京泰德制药股份有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-110804022-A | Preparation method of dexrazoxane | 扬子江药业集团有限公司 | 2020-02-18 | — | — | CN | disclosed |