Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662240 | 0.92 | PPARD (0.43) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL22829501 | 0.92 | KDM4E (0.45) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL28660037 | 0.90 | PPARD (0.49) | PPARDPPARGPPARASLC6A4HRH3 | |
| SCHEMBL1744826 | 0.89 | PPARD (0.55) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL1744825 | 0.89 | PPARD (0.55) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL1744830 | 0.89 | PPARD (0.55) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552762 | 0.88 | PPARD (0.54) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552764 | 0.88 | PPARD (0.54) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552765 | 0.88 | PPARD (0.54) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552763 | 0.88 | PPARD (0.47) | KDM4EALDH1A1TDP1PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114727976-A | Use of PPAR-delta agonists in the treatment of renal disease | 雷内奥制药公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113747891-A | Use of PPAR delta agonists in the treatment of Fatty Acid Oxidation Disorders (FAOD) | 雷内奥制药公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113710683-A | Use of PPAR-delta agonists in the treatment of mitochondrial myopathy | 雷内奥制药公司 | 2021-11-26 | — | — | CN | disclosed |