Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553795 | 0.94 | PPARD (0.45) | KDM4EALDH1A1TDP1PPARDLMNA | |
| SCHEMBL28680141 | 0.92 | PPARD (0.45) | KDM4EALDH1A1TDP1PPARDLMNA | |
| SCHEMBL28655199 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1TDP1PPARDLMNA | |
| SCHEMBL16553576 | 0.92 | MAPK14 (0.44) | KDM4EALDH1A1TDP1PPARDLMNA | |
| SCHEMBL1744826 | 0.91 | PPARD (0.55) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL1744825 | 0.91 | PPARD (0.55) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL1744830 | 0.91 | PPARD (0.55) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552762 | 0.90 | PPARD (0.54) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552765 | 0.90 | PPARD (0.54) | KDM4EALDH1A1TDP1PPARDPPARG | |
| SCHEMBL16552764 | 0.90 | PPARD (0.54) | KDM4EALDH1A1TDP1PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3756661-A1 | USE OF A PPAR-DELTA AGONIST FOR TREATING MUSCLE ATROPHY | vTv Therapeutics LLC (US) | 2020-12-30 | — | — | EP | disclosed |