SCHEMBL28655417

SCHEMBL28655417

O=C1CCc2cc(-c3ccc4c(c3)CCC4)ccc21

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.65
CYP11B1 P15538 2/20 0.55
CYP11B2 P19099 2/20 0.55
CYP1A2 P05177 1/20 0.55
MAOA P21397 3/20 0.53
MAOB P27338 3/20 0.53
PRKCI P41743 1/20 0.53
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PGR P06401 2/20 0.47
CYP2A6 P11509 1/20 0.46
GRM5 P41594 2/20 0.45
BAZ2B Q9UIF8 1/20 0.44
PBRM1 Q86U86 1/20 0.43
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456099 1.00 HSD17B1 (0.65) HSD17B1CYP11B1CYP11B2CYP1A2MAOA
SCHEMBL28655414 0.88 HSD17B1 (0.78) HSD17B1CYP11B1CYP11B2CYP1A2MAOA
SCHEMBL7584101 0.80 HSD17B1 (0.73) HSD17B1CYP11B1CYP11B2CYP1A2MAOA
SCHEMBL29541304 0.79 CYP11B1 (0.55) HSD17B1CYP11B1CYP11B2HSD17B10MEN1
SCHEMBL28655422 0.79 CYP11B1 (0.55) HSD17B1CYP11B1CYP11B2HSD17B10MEN1
SCHEMBL1745161 0.79 HSD17B1 (0.71) HSD17B1CYP11B1CYP11B2CYP1A2CASP1
SCHEMBL4418225 0.79 HSD17B1 (0.71) HSD17B1CYP11B1CYP11B2CYP1A2MAOA
SCHEMBL8170785 0.79 HSD17B1 (0.71) HSD17B1CYP11B1CYP11B2CYP1A2MAOA
SCHEMBL7506302 0.79 HSD17B1 (0.71) HSD17B1CYP11B1CYP11B2CYP1A2MAOA
SCHEMBL4090561 0.79 HSD17B1 (1.00) HSD17B1CYP11B1CYP11B2CYP1A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651784-B Synthesis method of 3,3', 4' -biphenyl tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2023-05-30 CN claimed
CN-113651784-B Synthesis method of 3,3', 4' -biphenyl tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2023-05-30 CN disclosed
CN-113651784-B Synthesis method of 3,3', 4' -biphenyl tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2023-05-30 CN disclosed
CN-113651784-A Synthetic method of 3,3',4,4' -biphenyl tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2021-11-16 CN disclosed